Pivotal Role of the Genital Epithelial Cells in HIV-1 Transmission

Author(s): Amelie De Saint Jean, Thomas Bourlet, Olivier Delezay

Journal Name: Current HIV Research

Volume 13 , Issue 6 , 2015


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Graphical Abstract:


Abstract:

AIDS remains one of the world’s most serious health challenges, with 35 million people living with HIV worldwide at the end of 2013. HIV sexual transmission accounts for the overwhelming majority of people newly infected, making genital and rectal mucosal tissues the major sites of infection. This review focuses on the role of the female genital epithelial cells in the establishment of HIV infection.

Keywords: Epithelial cells, female genital tract, HIV-1, innate immunity, microbicides, semen, sexually transmitted agents.

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Article Details

VOLUME: 13
ISSUE: 6
Year: 2015
Published on: 17 August, 2015
Page: [479 - 489]
Pages: 11
DOI: 10.2174/1570162X13666150624100339
Price: $65

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