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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Cyclization: A Useful Approach for the Synthesis of Nitrogen Heterocyclic N-Oxides

Author(s): Ning Liu, Yuan-Jie Shu, Bo-Zhou Wang, Xiang-Zhi Li and Fu-Qiang Bi

Volume 19, Issue 19, 2015

Page: [1896 - 1915] Pages: 20

DOI: 10.2174/1385272819666150622174626

Price: $65

Abstract

Nitrogen heterocyclic N-oxides attract enormous interest in synthetic chemistry, medicinal chemistry, functional materials and energetic materials. Cyclization reaction turns out to be an important and highly rewarding protocol for the construction of N-heterocyclic N-oxides and different types of organonitrogen compound could be utilized as crude materials. In this work a review of recent advancement in the generation of pyrazole, imidazole, triazole, triazine, tetrazine, isoquinoline and other N-heterocyclic N-oxides and their derivatives via cyclization reactions is presented.

Keywords: Nitrogen heterocyclic N-oxides, cyclization, mechanism, synthesis.

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