Tetracyclic Triterpenoids in Herbal Medicines and their Activities in Diabetes and its Complications

Author(s): Kaiser Hamid, Ali Alqahtani, Moon-Sun Kim, Jun-Lae Cho, Pei H. Cui, Chun Guang Li, Paul W. Groundwater, George Q. Li

Journal Name: Current Topics in Medicinal Chemistry

Volume 15 , Issue 23 , 2015

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Graphical Abstract:


Tetracyclic triterpenoids, including the dammarane, cucurbitane, cycloartane, lanostane and protostane groups, is a class of triterpenoids widely distributed in various medicinal plants, particularly those commonly used for the treatment of diabetes and its complications, such as Panax ginseng, Panax quinquefolium, Panax notoginseng, Gynostemma pentaphyllum, Astragalus membranaceus, Momordica charantia, and Ganoderma lucidum. This review highlights recent findings on the chemistry and bioactivities of tetracyclic triterpenoids from these plants and other popular herbal medicines.

Keywords: Astragalus, diabetes, Diabetic complications, Ginseng, Gynostemma, Herbal medicines, Tetracyclic triterpenoids.

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Article Details

Year: 2015
Published on: 21 August, 2015
Page: [2406 - 2430]
Pages: 25
DOI: 10.2174/1568026615666150619141940
Price: $65

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