Background: The aim of this study was to assess serum levels of highly
sensitive C-reactive protein (hs-CRP) and adiponectin in subjects with metabolic
syndrome and control groups.
Methods: There were 40 subjects with metabolic syndrome and 40 control groups.
Mean serum level of adiponectin and high sensitive C reactive protein were lower and
higher in subjects with metabolic syndrome than control groups, respectively. There
were significant positive correlation between high sensitive C reactive protein and
waist circumference, systolic and diastolic blood pressure, triglyceride and fasting
blood glucose. There were significant negative correlation between adiponectin and
waist circumference and triglyceride. Hs-CRP showed a stronger association with
metabolic syndrome than adiponectin.
Results: Our findings suggest that elevated hs-CRP and reduced adiponectin showed positive and
negative association with some metabolic syndrome components. Hs-CRP showed a stronger association
with the metabolic syndrome than adiponectin.
Conclusion: It seems that hs-CRP may play a significant role as a risk factor for metabolic syndrome. In
this study, in contrast with other findings it may suggest that hs-CRP is more important as a diagnostic
biomarker for metabolic syndrome than adiponectin. These differences may be due to the changes in the
lifestyle and dietary habits in subjects with metabolic syndrome in Gorgan inhabitants. It likes that these
subjects do less physical activity and use more fatty nutrients. It seems that subjects with metabolic
syndrome need to change their life style and dietary habits in this area to halt the burden of cardiovascular