Multidimensional Ophthalmic Nanosystems for Molecular Detection and Therapy of Eye Disorders

Author(s): Swati Vyas, Pratik Kakade, Manasi Chogale, John Disouza, Vandana Patravale

Journal Name: Current Pharmaceutical Design

Volume 21 , Issue 22 , 2015

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Symptomatic distresses associated with common ophthalmic infections and their persistence, have remained a tribulation with repeated occurrences. Although being a directly accessible organ, traditional therapeutic strategies exhibiting seemingly fruitful outcome in treatment and prognosis of eye disorders call for improvement in disease intervention. This is due to frequent challenges presented by the ophthalmic environment. Contemporary research has addressed these challenges by applying nanotechnology as a central concept in designing more proficient diagnostic and therapeutic systems for eye ailments. Within such nanosystems (dendrimers, aptamers, metal nanoparticles, etc.), bioactive agents, drugs and genetic materials can be entrapped and these form the key elements that act at the biomolecular stage and bestow a high level of efficacy towards eradication of disease causatives and specificity for recognition and capture aiding diagnostic processes. In the current review, we present researched and patented nanocentric technologies as promising tools in detection and treatment of ophthalmic ailments.

Keywords: Diagnosis, drug delivery, nanosystems, nanotherapeutic modules, ophthalmics.

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Article Details

Year: 2015
Published on: 13 July, 2015
Page: [3223 - 3238]
Pages: 16
DOI: 10.2174/1381612821666150531171052
Price: $65

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PDF: 35