The data associating blood pressure to salt intake in humans comes from randomized
clinical trials of interventions on dietary salt intake and population studies. Generally, estimates from
meta-analyses are similar to those derived from prospective population studies (1.7 mm Hg change in
systolic blood pressure per 100 mmol change in 24-hour urinary sodium). This observation, however,
does not translate into a higher risk of incidence rate of hypertension in individuals consuming a highsalt
diet. On the other hand, prospective studies relating cardiovascular outcomes to 24-h urinary sodium excretion produced
inconsistent conclusions. Thus, available evidence does not support current recommendations of an indiscriminate and
generalized reduction of salt intake in the general population.
Keywords: Blood pressure, cardiovascular mortality, cardiovascular outcomes, salt restriction, salt, sodium.
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