Simple and Efficient Route Toward Ambient Preparation of Pyrimido[b]Quinolinetriones Using Copper (I) Iodide Nanoparticles in Aqueous Media

Author(s): Shahrzad Abdolmohammadi, Zahra Aghaei-Meybodi

Journal Name: Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 18 , Issue 9 , 2015

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Abstract:

A simple and efficient synthesis of pyrimido[b]quinolinetriones is introduced using copper (I) iodide nanoparticles (CuI NPs) as an efficient heterogeneous catalyst in green media-water. The catalyst was prepared through the simple precipitation route and well characterized by various techniques such as XRD and SEM. The mild reaction conditions, using aqueous medium, reusability of the catalyst, simple reaction work-up and excellent yields of products make the present protocol sustainable and advantageous compared to the conventional methods.

Keywords: Aqueous media, CuI nanoparticles (CuI NPs), pyrimido[5, 4-b]quinolinetriones, tandem Knoevenagel-Michael condensation.

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Article Details

VOLUME: 18
ISSUE: 9
Year: 2015
Page: [911 - 916]
Pages: 6
DOI: 10.2174/1386207318666150525094234
Price: $65

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