Synthesis and Cytotoxicity of 4-(2-Adamantyl)phenylalkylamines

Author(s): Ioannis Papanastasiou, Stefanos Riganas, George B. Foscolos, Andrew Tsotinis, Samar A. Akhtar, Mohsin A. Khan, Khondaker M. Rahman, David E. Thursto

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 5 , 2015


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Abstract:

The design and synthesis of 4-(2-adamantyl)phenylalkylamines 1-4 are described and their antiproliferative activity against four different tumor cell lines is reported.

Keywords: C-2 substituted adamantane, 4-(2-adamantyl)phenylalkylamines, antiproliferative activity.

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Article Details

VOLUME: 12
ISSUE: 5
Year: 2015
Published on: 09 May, 2015
Page: [319 - 323]
Pages: 5
DOI: 10.2174/157017861205150509202419
Price: $65

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