Malondialdehyde (MDA) is one of the most common biomarkers of oxidative stress and is
used for the diagnosis of many diseases. This work aims to review the reaction used for the derivatization
of MDA, the parameters affecting adduct formation, and a number of recently published analytical
methods for quantification of MDA in biological samples. A brief discussion of the reliability of MDA
as an oxidative stress biomarker is also provided.
Keywords: Oxidative stress, biomarker, malondialdehyde, serum analysis, bioanalysis, review.
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