Fluoroquinolones are well known and among most promising nitrogen containing heterocyclic
compounds depicting broad spectrum and potent anti-infective activities. Numerous fluoroquinolone
derivatives have been found to possess considerable favorable properties such as excellent
bioavailability, good tissue penetrability and low toxic effects which attract the extensive research endeavors
worldwide. With a better understanding of structure activity relationships of fluoroquinolones,
it has been possible to develop superior compounds. This paper is an attempt to review the recent patents
on these drugs with special emphasis on ciprofloxacin, norfloxacin, ofloxacin and moxifloxacin.
Keywords: Antiinfectives, fluoroquinolones, infection, microbes, patents, pharmacokinetics.
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