An Insight into Patents of Fluoroquinolone Derivatives

Title:An Insight into Patents of Fluoroquinolone Derivatives

Volume: 12 Issue: 10

Author(s): Prabodh Chander Sharma, Mona Piplani and Harish Rajak

Affiliation:

Keywords: Antiinfectives, fluoroquinolones, infection, microbes, patents, pharmacokinetics.

Abstract: Fluoroquinolones are well known and among most promising nitrogen containing heterocyclic compounds depicting broad spectrum and potent anti-infective activities. Numerous fluoroquinolone derivatives have been found to possess considerable favorable properties such as excellent bioavailability, good tissue penetrability and low toxic effects which attract the extensive research endeavors worldwide. With a better understanding of structure activity relationships of fluoroquinolones, it has been possible to develop superior compounds. This paper is an attempt to review the recent patents on these drugs with special emphasis on ciprofloxacin, norfloxacin, ofloxacin and moxifloxacin.

Cite this article as:

Chander Sharma Prabodh, Piplani Mona and Rajak Harish, An Insight into Patents of Fluoroquinolone Derivatives, Letters in Drug Design & Discovery 2015; 12 (10) . https://dx.doi.org/10.2174/1570180812666150429234635