A new methods for the synthesis of molecular pockets, molecular umbrellas as well as
quasi podands of steroids derivatives have been described. Moreover, a molecular umbrellas and
pockets derived from biogenic precursors and their applications are described. Intermolecular 1,3-
dipolar cycloaddition gave a quasi podands with 1,2,3-triazole rings. The structures of the products
were confirmed by spectral analysis, mass spectrometry and PM5 semiempirical methods. Estimation
of the pharmacotherapeutic potential of synthesized compounds has been accomplished on the basis of
Prediction of Activity Spectra for Substances (PASS).
Keywords: Bile acids, molecular pockets, molecular umbrellas, PASS, PM5, quasi podands, sterols.
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