Molecular Mechanism and Targets of the Antimicrobial Activity of Metal Nanoparticles

Author(s): Faik N. Oktar, Mehmet Yetmez, Denisa Ficai, Anton Ficai, Florica Dumitru, Alexandra Pica

Journal Name: Current Topics in Medicinal Chemistry

Volume 15 , Issue 16 , 2015

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Abstract:

The emergence of multi-resistant bacteria to drugs is recognized as a major cause of the increasing number of deaths in hospitals. Killing these bacteria require multiple expensive drugs that can have side effects. Metal nanoparticles may provide a new strategy to combat them. Due the antimicrobial and antiviral properties, nanoparticles (NPs) have outstanding biological properties that can be handled properly for desired applications. This review presents antibacterial and antiviral activity of metal NPs, including the molecular mechanisms by which NPs annihilate multidrug-resistant bacteria.

Keywords: Antibacterial, Antiviral, Drug-multiresistant bacteria, Molecular mechanism.

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Article Details

VOLUME: 15
ISSUE: 16
Year: 2015
Page: [1583 - 1588]
Pages: 6
DOI: 10.2174/1568026615666150414141601
Price: $65

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