Title:The Ambidextrous Cyclooxygenase: An Enduring Target
VOLUME: 13 ISSUE: 6
Author(s):Mayank Bapna and Lalit Singh Chauhan
Affiliation:Department of Pharmaceutical Chemistry, Shivam Pharmaceutical Studies and Research Center, Anand-Sojithra Road, Valasan, Anand-Gujarat, India.
Keywords:Anticancer, COX, COX-3, cyclooxygenase, inflammation, NSAIDs, pain.
Abstract:With the discovery of COX, pain has not been treated in a relentless manner. Numbers of
drugs with fewer side effects were discovered and are used successfully for treatment of pain. With
new research coming into being since the discovery of COX, it was established that COX can be
targeted not only for treatment of pain but for curing various diseases like cancer, Alzheimer’s,
Parkinson’s disease, Glaucoma etc. With the sighting of COX-3, another isoform of COX, new
diseases are being targeted for better treatment.