A Novel Multi-functional Fluorescent Probe for Cu2+, Fe3+ and Ag+ Based on a Pyrimidine Thiourea Derivative

Author(s): Hassan H. Hammud, Mohammad H. El-Dakdouki, Nada Sonji, Ghassan Sonji, Kamal H. Bouhadir

Journal Name: Current Analytical Chemistry

Volume 11 , Issue 4 , 2015


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Abstract:

A multi-functional “turn-off” fluorescent probe, N-[[(6-Amino-1,2,3,4-tetrahydro-1,3- dimethyl-2,4-dioxo-5-pyrimidinyl)amino]thioxomethyl]- benzamide, was synthesized and characterized. The probe showed high sensitivity and selectivity towards copper(II), iron(III) and silver(I) ions via quenching of its fluorescence. The detection limits were found to be 4.0 – 16.0 ppb for the assayed cations. The thiourea linked uracil fluorescent probe is proved to be sensitive, selective, applicable in real samples and promise for practical applications.

Keywords: 5, 6-diamino-1, 3-dimethyluracil, fluorescent probe, silver, ferric, cupric ion, sensor.

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Article Details

VOLUME: 11
ISSUE: 4
Year: 2015
Published on: 24 March, 2015
Page: [279 - 290]
Pages: 12
DOI: 10.2174/1573411011666150324231041
Price: $65

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