In this study, multi-walled carbon nanotubes (MWCNTs) and vitamin B12 (VB12) were
fabricated on the surface of glassy carbon electrode (GCE). This modified electrode
(MWCNTs/VB12/GCE) was designed to determine p-hydroxyacetophenone (p-HYD) by square wave
voltammetry. The MWCNTs/VB12 film was characterized by Electrochemical impedance spectroscopy
and Fourier transform infrared spectroscopy, which exhibited excellent electrocatalytic activity
toward p-HYD by using square wave voltammetry. The peak current was linear with the concentration
of p-HYD over the range of 0.5 - 250 µM with the detection limit of 0. 15 µM (S/N = 3). Furthermore, this proposed sensor
has also demonstrated good reproducibility, high stability and excellent anti-interference ability.