IL-1 as a target in inflammation

Author(s): Yuki Ito, Naoe Kaneko, Tomoyuki Iwasaki, Shinnosuke Morikawa, Kentaro Kaneko, Junya Masumoto

Journal Name: Endocrine, Metabolic & Immune Disorders - Drug Targets
(Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders)

Volume 15 , Issue 3 , 2015

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Abstract:

Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various factors are thought to be involved in the pathological changes in tissues caused by inflammation. Interleukin 1, an inflammatory cytokine, is thought to have diverse physiological functions and to play an important role in inflammatory disease. In this review, we discuss interleukin-1 as a target of inflammatory disease.

Keywords: Infectious diseases, inflammasome, inflammation, interleukin-1β, receptors, tissue.

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Article Details

VOLUME: 15
ISSUE: 3
Year: 2015
Page: [206 - 211]
Pages: 6
DOI: 10.2174/1871530315666150316123657
Price: $65

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