Evolving Important Role of Lutetium-177 for Therapeutic Nuclear Medicine

Author(s): Ambikalmajan M.R. Pillai, Furn F. (Russ) Knapp

Journal Name: Current Radiopharmaceuticals

Volume 8 , Issue 2 , 2015


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Abstract:

Lutetium-177 (177Lu) is a late entrant into the nuclear medicine therapy arena but is expected to become one of the most widely used therapeutic radionuclides. This paper analyses the reason for the increasing preference of 177Lu as a therapeutic radionuclide. While the radionuclidic properties favor its use for several therapeutic applications, the potential for large scale production of 177Lu is also an important aspect for its acceptability as a therapeutic radionuclide. This introductory discussion also summarizes some developing clinical uses and suggested future directions for applications of 177Lu.

Keywords: Antibodies, bone pain palliation, isotope production, Lutetium-177, peptides, targeted radionuclide therapy, therapeutic radiopharmaceuticals.

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Article Details

VOLUME: 8
ISSUE: 2
Year: 2015
Published on: 18 August, 2015
Page: [78 - 85]
Pages: 8
DOI: 10.2174/1874471008666150312155959
Price: $65

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