Atherosclerosis and Cardiovascular Diseases
Pp. 139-148 (10)
A.K.M. Shamsuddin and Guang-Yu Yang
Atherosclerotic cardiovascular disease results in serious life threatening
conditions such as heart attack, stroke etc. Hypercholesterolemia is a risk factor; studies
show that InsP6 can lower serum cholesterol level. Oxidative damage seems to play an
important role in the pathogenesis of atherosclerosis as well as in heart attack. Studies
show that InsP6 by virtue of its antioxidant function can prevent or ameliorate some of
the deleterious sequel.
Atheroma, cholesterol, HDL, heart attack, hypercholesterolemia,
LDL, myocardial infarction, reperfusion injury, ROS, stroke, thrombosis.
The University of Maryland School of Medicine 10 S. Pine Street, MSTF-700 Baltimore, MD 21201-1116 USA., Northwestern University Feinberg School of Medicine 303 E Chicago Ave, Ward 4-115 Chicago, IL 60611 USA.