Analysis & Assays of Inositol and Inositol Phosphates
Pp. 50-56 (7)
A.K.M. Shamsuddin and Guang-Yu Yang
While the quantitation of inositol in biological specimens and that of InsP6 in
food is rather simple and the methodologies are well-established, accurate quantitation
of inositol phosphates, especially InsP6 in biological specimens in vivo has not been
easy, many being dogmatic about even its presence in human tissues. In spite of that, it
appears that finally accurate and specific methods to quantitate and follow InsP6 in
cells, tissues, plasma, urine etc. may have been developed that might be useful in both
research and clinical laboratories.
Fluorescence, HPLC, gas chromatography, GC-MS, ion-exchange
The University of Maryland School of Medicine 10 S. Pine Street, MSTF-700 Baltimore, MD 21201-1116 USA., Northwestern University Feinberg School of Medicine 303 E Chicago Ave, Ward 4-115 Chicago, IL 60611 USA.