Vaccines against Cysticercosis: A Revisited Review Focusing on Taenia solium
Pp. 313-335 (23)
Edda Sciutto, Gladis Fragoso, Marisela Hernández, Gabriela Rosas, Carlos Larralde and Sergio Rosales-Mendoza
Taenia solium cysticercosis is a major parasitic disease that severely affects
human health and the economy of undeveloped countries. Since pigs are obligate
intermediate hosts, it is plausible to curb human transmission by reducing pig
cysticercosis through effective vaccination. This article reviews the current knowledge
on the development of vaccines against porcine cysticercosis. It highlights the
development of plant-based, needle-free vaccine versions as a feasible and affordable
approach to reduce the logistic costs of injectable vaccines, while preventing the
digestive hydrolysis of vaccine antigens.
Anti-cestodiasis vaccine, cestode prevention, cysticercosis, infectious
diseases, multiepitope vaccines, neurocysticercosis, oral vaccination, poverty,
recombinant vaccines, rural communities, S3Pvac, subcutaneous vaccination,
synthetic vaccines, Taenia solium, transgenic plants, transmission control,
transplantomic cells, TSOL18, vaccine delivery, vaccine field trial, vaccines.
Instituto de Investigaciones Biomédicas, A.P. 70228; 04510 México, D.F., México.