A simple, efficient, and environmentally benign procedure for the synthesis of 2-amino-4Hchromene
ring has been achieved by the three-component reaction of an aromatic aldehyde,
malononitrile and diverse enolizable C-H activated compound under ultrasound irradiation using
sodium carbonate as a catalyst in aqueous media. Sodium carbonate as a natural salt, being available as
an inexpensive catalyst combined with ultrasound method promoted this protocol in comparison to
other methods and catalysts.
Keywords: Coumarin, dimedone, green synthesis, naphthol, sodium carbonate.
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