N-Methyl-2-Chloropyridinium Iodide/NaNO2/Wet SiO2: Neutral Reagent System for the Nitration of Activated Aromatic Compounds under Very Mild Conditions

Author(s): Roya Azadi, Zahra Nazari-Far

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 2 , 2015

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Graphical Abstract:


Mononitration of activated aromatic compounds using N-methyl-2-chloro-pyridinium iodide (Mukaiyama reagent)/ NaNO2/wet SiO2 reagent system under neutral, very mild and environmentally safer reaction condition has been developed. Various structurally diverse aromatic rings are subjected in this condition and the corresponding nitro-aromatic compounds are prepared in moderately high yields.

Keywords: Aromatic compounds, mukaiyama reagent, N-methyl-2-chloropyridinium iodide, nitration, sodium nitrite.

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Article Details

Year: 2015
Page: [136 - 140]
Pages: 5
DOI: 10.2174/157017861202150213105836
Price: $65

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PDF: 61