Mononitration of activated aromatic compounds using N-methyl-2-chloro-pyridinium iodide (Mukaiyama reagent)/
NaNO2/wet SiO2 reagent system under neutral, very mild and environmentally safer reaction condition has been developed.
Various structurally diverse aromatic rings are subjected in this condition and the corresponding nitro-aromatic
compounds are prepared in moderately high yields.
Keywords: Aromatic compounds, mukaiyama reagent, N-methyl-2-chloropyridinium iodide, nitration, sodium nitrite.
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