Recent Patents on Peptide Self-Assembled Hydrogels as Nanostructured Biomaterials

Author(s): Silvia Marchesan

Journal Name: Recent Patents on Nanomedicine (Discontinued)

Volume 4 , Issue 2 , 2014

Graphical Abstract:


Abstract:

This mini-review examines key classes of short peptides capable of self-assembly into nanostructured hydrogels for biomaterial applications, with an eye for the current patent landscape. Systems reviewed are the ones based on heterochiral short peptides, N-protected peptides with aromatic moieties to induce π-π stacking (e.g., Fmoc, naphthalene), peptide amphiphiles displaying alkyl chains, amphiphilic peptides, beta-hairpin systems. Patents related to their more general use in cell culture or more tissue-specific applications are also briefly discussed. Concluding remarks on current and future developments will provide a perspective on the direction that this field is undertaking.

Keywords: Amphiphiles, biomaterials, cell culture, Fmoc, hydrogel, naphthalene, peptides, self-assembly.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 4
ISSUE: 2
Year: 2014
Page: [77 - 81]
Pages: 5
DOI: 10.2174/1877912305666150213001402
Price: $58

Article Metrics

PDF: 12