Sodium Benzenesulfinates: Novel and Effective Organo Catalyst for Three Component Synthesis 5,6,7,8-Tetrahydro-4H-chromene Derivatives Under Ultrasound Irradiation

Author(s): Mehdi Abaszadeh, Mohammad Seifi

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 4 , 2015

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Graphical Abstract:


Sodium benzenesulfinates, as a new organo catalyst, can be used to synthesize tetrahydro- 4H-chromene derivatives by three component reaction of cyclic β-dicarbonyl compounds, malononitrile, and aromatic aldehydes, in H2O/EtOH, under ultrasound irradiation at room temperature. Inexpensiveness, stability and the potential of being easily obtained can be noted as preponderance of these catalysts. Furthermore, high conversions, short reaction times and cleaner reaction profiles are some of the advantages of this method. Moreover, H2O/EtOH (7:3) was selected as a green solvent.

Keywords: Sodium benzenesulfinates, tetrahydro-4H-chromene derivatives, three component reactions, ultrasound irradiation, cyclic β-dicarbonyl compounds, aromatic aldehydes.

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Article Details

Year: 2015
Published on: 24 March, 2015
Page: [271 - 276]
Pages: 6
DOI: 10.2174/1570178612666150203004727
Price: $65

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