Amberlyst-15 as a Highly Efficient and Reusable Catalyst for Direct C-S Bond Formation: Synthesis of Barbituryl Carbamodithioates

Author(s): Madhuri M. Sontakke, Chandrakant S. Bhaskar, Baliram N. Berad, Madhukar G. Dhonde

Journal Name: Letters in Organic Chemistry

Volume 12 , Issue 2 , 2015

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Abstract:

The C-S bond formation reaction has been described by the reaction of Bromo-barbituric acid with ammonium aryl dithiocarbamates in the presence of Amberlyst-15 as a reusable catalyst in aqueous medium. The mild reaction conditions, easy product isolation and good to high yields, are the major advantages of present protocol.

Keywords: Aqueous synthesis, Amberlyst-15, ammonium aryl dithiocarbamates, antimicrobial activities, 5-bromobarbituric acid, 1-phenyl-5-bromobarbituric acid.

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Article Details

VOLUME: 12
ISSUE: 2
Year: 2015
Page: [115 - 121]
Pages: 7
DOI: 10.2174/1570178612666150108002716
Price: $65

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