Regioselective Nitration of Phenols and Phenyl Ethers Using Aluminium Nitrate on Silica as a Nitrating System

Title:Regioselective Nitration of Phenols and Phenyl Ethers Using Aluminium Nitrate on Silica as a Nitrating System

Volume: 12 Issue: 2

Author(s): Mahadeo R. Patil, Pravinkumar H. Mohite, Suresh Shisodia and Rangappa S. Keri

Affiliation:

Keywords: Phenol, nitration, regioselective, aluminum nitrate, silica.

Abstract: Silica supported aluminum nitrate (Al(NO3)3·9H2O) was found to be an excellent reagent for the nitration of phenols and phenyl ethers. This procedure works efficiently on most of the examples at room temperature yielding nitro derivatives in fair to good yields with high regioselectivity. The present methodology evidenced a considerable enhancement in the reaction rate along with high o-selectivity, excellent yields, ease of handling and the simplicity in work up.

Cite this article as:

R. Patil Mahadeo, H. Mohite Pravinkumar, Shisodia Suresh and S. Keri Rangappa, Regioselective Nitration of Phenols and Phenyl Ethers Using Aluminium Nitrate on Silica as a Nitrating System, Letters in Organic Chemistry 2015; 12 (2) . https://dx.doi.org/10.2174/1570178612666150108000402