Abstract
Since, the first report on cosmetic applications of non-ionic surfactant vesicles by L’Oreal, numerous papers have been published reporting success of niosomes in drug delivery. Niosomes are considered as one of the most successful drug carrier system applying nanotechnology to potentiate the therapeutic efficacy and reduce toxicities of conventional therapies. Niosomes are biodegradable, nontoxic and nonionic surfactants based vesicular drug carriers. The recent advancements in the pharmaceutical research are focused on the development of new delivery systems based on micro or nano-sized carriers to modulate the drug delivery, targeting as well as to improve the drug stability. Niosome are effective drug carrier with the ability of encapsulating both lipophilic and hydrophilic drugs. This laconic review exhaustively focuses on the potential of niosomal drug delivery with special emphasis on their role in drug targeting, advantages and disadvantages, formulation approaches and applications of niosomes in the disease therapy.
Keywords: Cholesterol, drug carrier systems, nanocarrier, niosomes, non-ionic surfactants, supercritical fluids.
Pharmaceutical Nanotechnology
Title:Frontier Lipid-Based Carrier Systems for Drug Targeting: A Laconic Review on Niosomes
Volume: 2 Issue: 3
Author(s): Rajendra Awasthi, Sumit Kumar and Giriraj T. Kulkarni
Affiliation:
Keywords: Cholesterol, drug carrier systems, nanocarrier, niosomes, non-ionic surfactants, supercritical fluids.
Abstract: Since, the first report on cosmetic applications of non-ionic surfactant vesicles by L’Oreal, numerous papers have been published reporting success of niosomes in drug delivery. Niosomes are considered as one of the most successful drug carrier system applying nanotechnology to potentiate the therapeutic efficacy and reduce toxicities of conventional therapies. Niosomes are biodegradable, nontoxic and nonionic surfactants based vesicular drug carriers. The recent advancements in the pharmaceutical research are focused on the development of new delivery systems based on micro or nano-sized carriers to modulate the drug delivery, targeting as well as to improve the drug stability. Niosome are effective drug carrier with the ability of encapsulating both lipophilic and hydrophilic drugs. This laconic review exhaustively focuses on the potential of niosomal drug delivery with special emphasis on their role in drug targeting, advantages and disadvantages, formulation approaches and applications of niosomes in the disease therapy.
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Awasthi Rajendra, Kumar Sumit and T. Kulkarni Giriraj, Frontier Lipid-Based Carrier Systems for Drug Targeting: A Laconic Review on Niosomes, Pharmaceutical Nanotechnology 2014; 2 (3) . https://dx.doi.org/10.2174/2211738503666150107234904
DOI https://dx.doi.org/10.2174/2211738503666150107234904 |
Print ISSN 2211-7385 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-7393 |
Call for Papers in Thematic Issues
Polymeric nanocarriers in drug delivery
Polymeric nanocarriers play a crucial role in drug delivery due to their versatility, and unique properties for targeting and modifying drug release. Their ability to enhance therapeutic outcomes, reduce side effects, and enable the delivery of drugs in a more targeted and controlled manner made them popular in the last ...read more
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