Since, the first report on cosmetic applications of non-ionic surfactant vesicles by L’Oreal, numerous
papers have been published reporting success of niosomes in drug delivery. Niosomes are considered
as one of the most successful drug carrier system applying nanotechnology to potentiate the therapeutic
efficacy and reduce toxicities of conventional therapies. Niosomes are biodegradable, nontoxic and nonionic
surfactants based vesicular drug carriers. The recent advancements in the pharmaceutical research are
focused on the development of new delivery systems based on micro or nano-sized carriers to modulate the drug delivery,
targeting as well as to improve the drug stability. Niosome are effective drug carrier with the ability of encapsulating both
lipophilic and hydrophilic drugs. This laconic review exhaustively focuses on the potential of niosomal drug delivery with
special emphasis on their role in drug targeting, advantages and disadvantages, formulation approaches and applications
of niosomes in the disease therapy.
Keywords: Cholesterol, drug carrier systems, nanocarrier, niosomes, non-ionic surfactants, supercritical fluids.
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