Physical Activity and Diabetic Cardiomyopathy: Myocardial Adaptation Depending on Exercise Load

Author(s): Solene Le Douairon Lahaye, Francoise Rannou Bekono, Tom Broderick

Journal Name: Current Diabetes Reviews

Volume 10 , Issue 6 , 2014

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Diabetes mellitus (DM), an increasing health problem worldwide, is associated with severe cardiovascular complications. To date, the beneficial effects of physical activity in both prevention and treatment of DM and its complications are well established. Nevertheless, it appears that exercise training, depending on the load, exerts differential effects on the myocardium. Hence, in this review, the impact of exercise training, focusing on exercise modalities and adaptations in response to load, on diabetic cardiovascular function, are discussed. Molecular mechanisms that may be involved in these adaptions to exercise training are also addressed.

Keywords: Cardiac function, diabetes, exercise load, physical activity, molecular mechanisms.

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Article Details

Year: 2014
Page: [371 - 390]
Pages: 20
DOI: 10.2174/1573399811666141229151421
Price: $65

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