Title:Nanodiamonds as a New Horizon for Pharmaceutical and Biomedical Applications
VOLUME: 12 ISSUE: 3
Author(s):Harsiddhi M. Chaudhary, Aindrilla S. Duttagupta, Kisan R. Jadhav, Sai V. Chilajwar and Vilasrao J. Kadam
Affiliation:University of Mumbai, Bharati Vidyapeeth’s College of Pharmacy, Department of Pharmaceutics, CBD Belapur, Sector-8, Navi-Mumbai-400614, India.
Keywords:Biocompatible, bioimaging, nanodiamonds, photoluminescent, surface functionalization, targeted delivery.
Abstract:A palpable need for the optimization of therapeutic agents, due to challenges tackled by
them such as poor pharmacokinetics and chemoresistance, has steered the journey towards novel interdisciplinary
scientific field for emergence of nanostructure materials as a carrier for targeted delivery
of therapeutic agents. Amongst various nanostructures, nanodiamonds are rapidly rising as promising
nanostructures that are suited especially for various biomedical and imaging applications. Advantage
of being biocompatible and ease of surface functionalization for targeting purpose, besides safety
which are vacant by nanodiamonds made them a striking nanotool compared to other nonmaterials
which seldom offer advantages of both functionality as well as safety. This review outlines the summary of nanodiamonds,
regarding their types, methods of preparation, and surface modification. It also portrays the potential applications
of nanodiamond as targeted drug delivery of various bioactive agents. Based on photoluminescent and optical property,
nanodiamonds are envisioned as an efficient bioimaging nanostructure. Nanodiamonds as a novel platform hold great
promise for targeting cancer cells and in-vivo cell imaging. Based upon their inimitable properties and applications nanodiamonds
propose an exciting future in field of therapeutics and thus possess vibrant opportunities.
