A mild, simple and efficient procedure for the preparation of 3,4-dihydropyrimidin-2(1H)-ones and 3,4,7,8-
tetrahydroquinazoline-2,5-diones is described using pyridinium p-toluenesufonate as an efficient catalyst under mild conditions.
Simple methodologies, easy work-up procedure, excellent yields and very short reaction times are among the
other advantages of this work.
Keywords: 3, 4, 7, 8-tetrahydroquinazoline-2, 5-diones, 3, 4-Dihydropyrimidin-2(1H)-ones, biginelli reaction, pyridinium-ptoluenesufonate.
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