Non-Invasive Assessment of Non-Alcoholic Fatty Liver Disease: Ultrasound and Transient Elastography

Author(s): Annalisa Berzigotti

Journal Name: Reviews on Recent Clinical Trials

Volume 9 , Issue 3 , 2014

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Graphical Abstract:


Non-alcoholic fatty liver disease (NAFLD) is extremely prevalent in the Western world. Non-invasive diagnostic methods should be able to reflect the presence and severity of liver fatty changes and the presence and severity of hepatic inflammation and fibrosis (features of non-alcoholic steato-hepatitis), since these are related to the risk of progression and clinical complications.

This article will: a) review the rational basis for the use of ultrasound and transient elastography in patients with NAFLD; b) summarize available data regarding the diagnostic performance of these two widely used non-invasive imaging methods in patients with NAFLD; and c) give an overview of newer sonographic applications that might be used in clinical practice in the near future in this field.

Keywords: ARFI, cirrhosis, controlled attenuation parameter, liver fibrosis, NASH, sonography.

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Article Details

Year: 2014
Published on: 15 December, 2014
Page: [170 - 177]
Pages: 8
DOI: 10.2174/1574887109666141216101630
Price: $65

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