Title:Functionalization of Non-Activated C-H Bonds in the Synthesis of Vitamin D Metabolites and Analogs
VOLUME: 14 ISSUE: 21
Author(s):Edelmiro Moman
Affiliation:ProSciens, 2 - 4 rue du Palais de Justice, L-1841 Luxembourg, Luxembourg.
Keywords:Analogs, calcitriol, Free radical, Non-activated carbons, Remote functionalization, Synthesis, Vitamin D.
Abstract:The development of non-microbial methods for the selective functionalization of non-activated C-H
bonds has constituted a challenge, with important economical and environmental implications, for chemists for
over a century. The present review provides a comprehensive and current compendium that illustrates the
power of C-H functionalization and, namely, of remote functionalization strategies, to expeditiously access vitamin
D analogs with intricate structures.
