Chromones (1-benzopyran-4-ones) are natural occurring compounds present in representative
amounts in a normal human diet and are associated with interesting physiological activities such as antiinflammatory,
antidiabetic, antitumor, anticancer etc. These biological activities are thought to be related to
the antioxidant properties of chromones i.e. to neutralize active oxygen and to cut off free radicals processes
that can delay or inhibit cell impairment which leads to various diseases. In this review, we have summarized
the literature reports published in about 70 research articles during the period January 2004 to March
2014 on more than 400 naturally as well as the synthetically derived chromone derivatives having antioxidant potential.
The literature reports suggest that the double bond, a carbonyl group of chromone and 3´,4´-dihydroxy group (catechol) in
ring B along with the C-3 and C-5 hydroxyl groups are important for radical scavenging activity. In turn, a decrease in the
radical scavenging potential has been observed upon methylation / glycosylation of the hydroxyl groups on chromone nucleus.