Signal transduction has been acknowledged to be involved in various cell biological processes.
And it is proved that multiple signaling pathways have been associated with the development and
progression of pancreatic cancer, which remains one of the most devastating human diseases. Newly
developed drugs targeting these aberrant signaling pathways show bright prospect in improving the
therapeutic efficacy and outcome for patients with pancreatic cancer. Here we overview the pancreatic
cancer related signaling pathway disorders and the corresponding promising targeted therapeutic regimens.