Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists

Author(s): Antonios Katsianis, Emmanouil Petrou, Anna Kostopoulou, George Theodorakis

Journal Name: Cardiovascular & Hematological Agents in Medicinal Chemistry
Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents

Volume 12 , Issue 1 , 2014

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Novel oral anticoagulants (NOACs) have been developed as alternatives for vitamin K antagonists (VKAs) for the prevention of thromboembolic events in patients with a variety of medical conditions. In this review, we summarize the current data on NOACs safety and efficacy compared to VKAs and in specific patients’ groups including heart valve replacement, venous thromboembolism, advanced renal failure and the elderly.

Keywords: Efficacy, novel oral anticoagulants, safety, vitamin K antagonists.

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Article Details

Year: 2014
Page: [9 - 13]
Pages: 5
DOI: 10.2174/187152571201141201092129
Price: $65

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PDF: 45