Title:Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists
VOLUME: 12 ISSUE: 1
Author(s):Antonios Katsianis, Emmanouil Petrou, Anna Kostopoulou and George Theodorakis
Affiliation:Division of Cardiology, Onassis Cardiac Surgery Center, 356 Syggrou Ave., GR-17674, Athens, Greece.
Keywords:Efficacy, novel oral anticoagulants, safety, vitamin K antagonists.
Abstract:Novel oral anticoagulants (NOACs) have been developed as alternatives for vitamin K antagonists (VKAs) for
the prevention of thromboembolic events in patients with a variety of medical conditions. In this review, we summarize
the current data on NOACs safety and efficacy compared to VKAs and in specific patients’ groups including heart valve
replacement, venous thromboembolism, advanced renal failure and the elderly.