Although the prevalence of Peyronie’s disease (PD) is reported to be 3-9% in men, the true
prevalence is likely higher due to under-reporting. Many treatment modalities have been described for
PD with varying degrees of success. In this article, we review and summarize the current literature
pertaining to all pharmacotherapies (oral, intralesional, iontophoresis, and topical) and minimally invasive
treatments available for PD (vacuum, traction device, shock wave therapy, and radiation treatment).
Additionally, we discuss emerging therapies for PD that are still in pre-clinical development,
including stem cell therapy.