Dearomatization Strategies of Heteroaromatic Compounds

Author(s): Gunasekar Ramachandran, Kulathu Iyer Sathiyanarayanan

Journal Name: Current Organocatalysis

Volume 2 , Issue 1 , 2015

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Graphical Abstract:


Dearomatization strategies of heteroaromatic compounds such as benzofurans, indoles, thiophenes, pyridines, and other heteroaromatic compounds afford the most efficient protocol for the synthesis of highly bioactive molecules, natural products and commercially available drugs. The use of these strategies has been significantly increased, which has fascinated several research groups as the dearomatization strategies of heteroaromatic compounds at C-2 & C-3 substitution leads to formation of numerous drug-like molecules. The recent developments in dearomatization strategies involving at C-2 & C-3 positions of various heteroaromatic compounds is discussed in this review.

Keywords: Benzofurans, dearomatization, furans and indoles, heteroaromatic.

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Article Details

Year: 2015
Published on: 25 February, 2015
Page: [14 - 26]
Pages: 13
DOI: 10.2174/2213337201666141110222735

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