Title:Green Synthesis of Phosphoryl-2-Oxo-2H-Pyran via Three Component Reaction of Trialkyl Phosphites
VOLUME: 17 ISSUE: 9
Author(s):Zinatossadat Hossaini, Fatemeh Sheikholeslami-Farahani and Faramarz Rostami-Charati
Affiliation:Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran.
Keywords:2H-pyran, Alky bromide, dialkyl acetylenedicarboxylates, green chemistry, three-component reaction, trialkyl
phosphite.
Abstract:An effective one-pot synthesis of dialkoxyphosphoryl-2-oxo-2H-pyran derivatives by three-component reaction
of alky bromides and dialkyl acetylenedicarboxylates in the presence of trialkyl phosphite is described. The reactions were
performed under solvent-free conditions at 50°C and neutral conditions and provided good yields of products.
