During the last decade, the formulation of nanofibrous materials loaded with different drugs for
biomedical applications has evoked considerable interest. The large specific surface area, the special micro- and macrostructure
of fiber mats, the possibility for gradual release and site-specific local delivery of the active compounds lead to
cytotoxicity decrease and enhancement of the therapeutic effect of drugs and implants. The present review details the different
spinning techniques applied for the design of micro- and nanofibrous drug delivery systems. It furthermore deals
with the use of various polymers that are capable for the formation of fiber scaffolds of various biomedical applications.
Keywords: Drug delivery, nano- and microfibers, polymers, regenerative medicine, spinning techniques, tissue engineering.
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