The host immune system is regulated not only by endogenous factors, such as cytokines and chemokines, but
also by exogenous factors, such as commensal bacteria and dietary materials. Vitamins are vital nutrients that are mainly
derived from the diet and commensal bacteria. Accumulating evidence has revealed specific functions of vitamins in the
control of host immunity. In agreement with their vital roles in the appropriate maintenance of immunity, excessive or
insufficient intake of vitamins leads to the development of immune diseases or susceptibility to infection. In this review,
we focus on the diverse but specific immunologic functions of vitamins in regulating host immune responses and their
association with immune and infectious diseases.
Keywords: Allergy, inflammation, mast cells, regulatory T cells, vitamins.
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