Applications of Mannich Reaction in Total Syntheses of Natural Products

Author(s): Majid M. Heravi, Vahideh Zadsirjan, Zahra Bozorgpour Savadjani

Journal Name: Current Organic Chemistry

Volume 18 , Issue 22 , 2014

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Graphical Abstract:


Mannich reaction has captured great attention and found usefulness as one of the most powerful synthetic methodologies for the carbon-carbon bond formation. Mannich reaction is also found to have a variety of applications in the total syntheses of natural and biologically active compounds in their crucial C-C bond forming steps. The present review is focused on the applications of Mannich reaction in total syntheses of natural products and some other complex targets.

Keywords: Alkaloid, Mannich reaction, natural product, total syntheses.

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Article Details

Year: 2014
Published on: 26 November, 2014
Page: [2857 - 2891]
Pages: 35
DOI: 10.2174/1385272819666141014212254
Price: $58

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