Mannich reaction has captured great attention and found usefulness as one of the most powerful synthetic
methodologies for the carbon-carbon bond formation. Mannich reaction is also found to have a variety of applications in
the total syntheses of natural and biologically active compounds in their crucial C-C bond forming steps. The present review
is focused on the applications of Mannich reaction in total syntheses of natural products and some other complex
Keywords: Alkaloid, Mannich reaction, natural product, total syntheses.
Rights & PermissionsPrintExport