Application of Ion Chromatography in Clinical Studies and Pharmaceutical Industry

Author(s): Rajmund Michalski

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 14 , Issue 10 , 2014

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Abstract:

Ion chromatography is a well-established regulatory method for analyzing anions and cations in environmental, food and many other samples. It offers an enormous range of possibilities for selecting stationary and mobile phases. Additionally, it usually helps to solve various separation problems, particularly when it is combined with different detection techniques. Ion chromatography can also be used to determine many ions and substances in clinical and pharmaceutical samples. It provides: availability of high capacity stationary phases and sensitive detectors; simple sample preparation; avoidance of hazardous chemicals; decreased sample volumes; flexible reaction options on a changing sample matrix to be analyzed; or the option to operate a fully-automated system. This paper provides a short review of the ion chromatography applications for determining different inorganic and organic substances in clinical and pharmaceutical samples.

Keywords: Clinical samples, drugs, human fluids, ion chromatography, ions, pharmaceutical samples, sample preparation.

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Article Details

VOLUME: 14
ISSUE: 10
Year: 2014
Page: [862 - 872]
Pages: 11
DOI: 10.2174/1389557514666141013142203
Price: $65

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