Ion chromatography is a well-established regulatory method for analyzing anions and cations in environmental,
food and many other samples. It offers an enormous range of possibilities for selecting stationary and mobile phases.
Additionally, it usually helps to solve various separation problems, particularly when it is combined with different
detection techniques. Ion chromatography can also be used to determine many ions and substances in clinical and
pharmaceutical samples. It provides: availability of high capacity stationary phases and sensitive detectors; simple sample
preparation; avoidance of hazardous chemicals; decreased sample volumes; flexible reaction options on a changing
sample matrix to be analyzed; or the option to operate a fully-automated system. This paper provides a short review of
the ion chromatography applications for determining different inorganic and organic substances in clinical and
Keywords: Clinical samples, drugs, human fluids, ion chromatography, ions, pharmaceutical samples, sample preparation.
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