Synthesis and Insecticidal Activity of Acylthiourea Derivatives from β-pinene

Title:Synthesis and Insecticidal Activity of Acylthiourea Derivatives from β-pinene

Volume: 12 Issue: 3

Author(s): Yanqing Gao*, Jian Li*, Shibin Shang and Dan Wang

Affiliation:

• Research & development center of biorational pesticide, College of Plant Protection, Northwest Agriculture and Forestry University, Yangling 712100,China

• College of Forestry, Northwest Agriculture and Forestry University, Yangling 712100, Shaanxi,China

Keywords: Acylthiourea derivatives, β-pinene, botanical insecticide, insecticidal activity.

Abstract: 4-isopropylcyclohexa-1, 3-dienecarboxylic acid (dehydrocumic acid) was prepared from β-pinene, and a series of acylthiourea derivatives was obtained. The structures of title compounds were characterized by FT-IR, NMR, and MS. The insecticidal activities against ostrinia furnacclis and bemisia tabaci were evaluated. The title compounds exhibited moderate larvicidal activity against ostrinia furnacclis. The preliminary study showed the introduction of orth and paro substitute displayed relatively good performance. The study promoted new application of β-pinene and its derivatives in pesticide management as botanical insecticide.

Cite this article as:

Gao Yanqing *, Li Jian *, Shang Shibin and Wang Dan , Synthesis and Insecticidal Activity of Acylthiourea Derivatives from β-pinene, Letters in Drug Design & Discovery 2015; 12 (3) . https://dx.doi.org/10.2174/1570180811666141009234615