Organocatalytic Domino Approaches for Enantioselective Formation of Six Membered Carbacycles

Author(s): Sauvik Samanta, Aditya Bhattacharyya, Subhomoy Das, Manas K. Ghorai

Journal Name: Current Organic Chemistry

Volume 18 , Issue 22 , 2014


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Abstract:

Stereoselective formation of six-membered carbacycles with biological and pharmaceutical relevance is one of the prime research areas in modern organic synthesis. Various innovative synthetic protocols involving asymmetric C-C bond forming reactions have been developed and exploited widely. The present review attempts to elaborate the original contributions and recent advancements made in this field for the stereoselective synthesis of a diverse array of asymmetric sixmembered carbacyclic compounds employing very simple and/or advanced organocatalytic domino reactions.

Keywords: Carbacycles, cascade, C-C bond formation, domino reaction, enantioselective, Michael reaction, organocatalysis, tandem.

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Article Details

VOLUME: 18
ISSUE: 22
Year: 2014
Published on: 26 November, 2014
Page: [2842 - 2856]
Pages: 15
DOI: 10.2174/1385272819666141009215403
Price: $58

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