Stem cell treatment or therapy is gaining interest as future medicine to treat several dreadful diseases/disorders. Especially
mesenchymal stem cells (MSCs) derived from both embryonic and adult cell sources have shown tremendous impact on improving
human health. These MSCs have evolved into intensely studied research subjects and clearly collected a great deal of
experimental data in the past decade. Even after all these years, research on MSCs still remains a hot and happening area with
lot many questions to be answered. In this direction, in our special issue we discussed the safety issue of MSCs as allogenic
transplant subject (Sarah Broeckx et al.) and their differentiation potential into cartilage (Vuk Savkovic et al.). We also discussed
how nanobiomaterials influence the stem cell modulation (Kiran Kumar Bokara) and how the signaling molecules and
signaling pathways influence MSCs fate in regenerative medicine (Rama Raju Baadhe et al. and Birru Bhaskar et al.). In this
special issue we also highlighted MSC’s interaction and interference with cancer cells (Chinnapandi Bharathiraja et al.). To the
end we discussed advanced bone marrow aspiration by perfusion reactor system.
Keywords: Biomaterials, cell based therapies, mesenchymal stem cells, regenerative medicine, tissue engineering.
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