Thixotropic and Injectable Nature of Supramolecular Aqueous Gels Derived from N,N'-Dibenzoyl-L-cystine and the Effects of Esterification

Author(s): Eva-Maria Schon, Jurgen Bachl, David Díaz Díaz

Journal Name: Nanoscience & Nanotechnology-Asia

Volume 4 , Issue 1 , 2014

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Abstract:

The thixotropic and injectable properties of physical aqueous gels derived from N,N'-dibenzoyl-L-cystine (1, DBC) and its dimethyl ester (2) at room temperature (RT) are described. The characterization of the materials was carried out by oscillatory rheological measurements, including thixotropy-loop tests, and field emission scanning electron microscopy (FE-SEM). Moreover, the effects of gelator concentration and added DMSO on the gel stability are also discussed. Interestingly, comparative studies revealed, among other effects, that esterification of DBC has a positive effect on both the critical gelation concentration (CGC(1) = 4.5 mM; CGC(2) = 2.0 mM) and the gel-to-sol transition temperature of the gels (Tgel(1) = 65 ºC; Tgel(2) = 78 ºC), whereas the thixotropic-response was significantly hampered.

Keywords: Esterification, gels, injectability, self-assembly, thixotropy.

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Article Details

VOLUME: 4
ISSUE: 1
Year: 2014
Page: [31 - 37]
Pages: 7
DOI: 10.2174/2210681204666140905222744
Price: $25

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