Inflammation is an important phenomenon in allergic disorders and corticosteroid drugs since their anti inflammatory
properties have a pivotal role in improvement, control and relieving the symptoms and signs of asthma, allergic
rhinitis, atopic dermatitis and many other inflammatory disorders. Nevertheless, the prescription of these drugs might
be associated with some unwanted reactions such as hyperglycemia, hypertension, Cushing's syndrome, adrenal insufficiency
and growth failure. In recent decades administration of intranasal and inhaled corticosteroids instead of systemic
parenteral or oral drugs reduced some of these concerns during treatment of patients and enable them to receive the effective
and safer kind of therapy in acute or chronic inflammatory disorders of nose and airways. In this article the properties
of inhaler (ICS) and intranasal corticosteroids (INCS) were reviewed.