Targeting Angiogenesis in Gastro-Intestinal Non Colorectal Cancers; A Review

Author(s): S.A. Brahmi, Y. Seddik, S. Afqir

Journal Name: Current Angiogenesis (Discontinued)

Volume 3 , Issue 2 , 2014

Graphical Abstract:


Angiogenesis is a key issue in the carcinogenesis progression. The development of anti-angiogenic targeted therapies has made significant progress over the last decade. Targeting angiogenesis is considered as a part of the treatment of metastatic colorectal cancer. Less data is available for the other gastrointestinal cancers. The objective of this article is to provide a review of the angiogenesis targeting drugs evaluated in gastrointestinal non colorectal cancers. The review is focused on the following 5 common gastrointestinal cancers: gastric, pancreatic, neuroendocrine cancers, biliary cancers, and hepatocellular carcinoma.

Keywords: Angiogenesis, gastro-intestinal cancers, targeted therapy.

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Article Details

Year: 2014
Published on: 08 January, 2015
Page: [80 - 87]
Pages: 8
DOI: 10.2174/2211552802666140820223621
Price: $58

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